Katalog inovačních příležitostí

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Úvod

Katalog inovačních příležitostí (KIP) je portfoliem sdružujícím produkty, specifické nabídky smluvního výzkumu a další formy investičních příležitostí ze všech fakult Univerzity Karlovy.


Každoročně evidujeme nové inovativní technologie a portfolio je tedy stále aktualizované. CPPT považuje za nejefektivnější formu spolupráce individuální kontakt s firmou, kdy identifikujeme specifické oblasti zájmu.


Níže vypsané technologie nejsou absolutním výčtem naší nabídky a proto rádi navážeme spolupráci s dalšími podniky. Kontakt

Introduction

Catalogue of innovation opportunities (KIP) is a portfolio associating products, special offers of contract research and other forms of investment opportunities covering all faculties of Charles University.


Every year we register new innovative technologies and the portfolio is constantly updated. CPPT considered as the most effective form of cooperation personal contact with the company, when we identify specific areas of your interest.


Below listed technologies are not an absolute list of our portfolio and we are pleased to establish cooperation with other companies. Contact

Portfolio

Heat Exchanger with Laminariser


Heat Exchanger with Laminariser is a new plastic product with a promising commercial potential filling in the gap on the market - especially  of healthcare and lab equipment  products related to cooling and heating of fluids. The product has been primarily developed as a single use medical device during blood cooling and  dialyzing  procedure,  as  a  support  to  patients with  such kidney disorders that this heat exchanger  method is absolutely necessary.  Nevertheless,   it can also  be used for cooling and heating of non-aggressive fluids in relatively small volumes.


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In vivo evaluation of antituberculotic activity of agents with efficacy against Mycobacterium tuberculosis


In cooperation with the Faculty of Pharmacy in Hradec Králové (Charles University in Prague), and the Centre of Biological Defence in Těchonín, the method entitled In vivo evaluation of antituberculotic activity of agents with efficacy against Mycobacterium tuberculosis – was developed and verified. In vivo tests using this method and the unique equipment are now available also for scientists from other scientific institutions as well as for scientists from development departments of private companies.


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Homebalance

Homebalance is an interactive system for home-based therapy of balance disorders. This therapeutic system is aimed for patients with balance and motor skill disorders. It is also useful in therapy of patients after orthopedic surgery. The system can likewise serve wheelchair users, who can exercise on the platform in a seated position. Homebalance is suitable for use in therapy of patients of any age category, in healthcare facilities or at home.


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Oxa- and thiadiazoles useful on the treatment of drug-susceptible and multidrug-resistant tuberculosis


A series of nitro-group containing oxa- and thiadiazoles with superior in vitro antitubercular activity (minimal inhibitory concentration = 0.03 – 0.5 µM), including multidrug-resistant species, with no cross-resistance with first and second line antituberculosis drugs, with low in vitro and in vivo toxicity. The institution seeks partners interested in further development of these highly active antitubercular agents.


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Bifunctional cyclam based ligands for conjugations with targeting vectors and their 64-Cu radiopharmaceuticals for PET imaging


Wide range of radioisotopes is used in nuclear medicine for diagnostic and therapeutic applications. In the recent years, a number of metal radioisotopes have been considered as they enable nuclear medicine utilizations exactly according to patient needs as defined by principles of “personalized medicine”; for such utilizations, also the term “theranostics” is used. These radioisotopes cannot be applied in a free form as, in such form, they are non- specifically deposited in tissues. Therefore, the metal radioisotopes must be bound by suitable organic compounds (“ligands”, or “chelators”) forming a stable complex which is not decomposed in body.


The presented cyclam based ligands combined with copper radioisotopes can be used for visualization of biodistribution of many biologically active compounds using PET imaging. By leveraging this novel theranostic approach, our compounds allow the determination of dose during the diagnostic stage with Copper-64 and delivers the right amount of radiation to the tumor for therapy with Copper-67.


New features:

  • completely new chelator family for copper radioisotopes

  • syntheses of bifunctional chelator with various reactive groups for conjugation reactions

  • synthetic precursor syntheses also patented

  • conjugation reactions were tested

  • radiolabelling with 64-copper is efficient (room temperature, small chelator excess) leading to a high specific activity

  • conjugation reaction conditions tested in water or water-organic solvent mixtures

  • click conjugation reactions tested

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ROTAPHONE - a mechanical sensor system for measuring seismic ground motions and a method of seismic measurement using this system


A measuring instrument, a combined seismic sensor system able to measure 6 components of seismic motion, i.e. 3 orthogonal translations components, 3 rotational components around the orthogonal axes  at a given measurement point. The instrument is suitable for measuring wave fields generated both by man-made sources (quarry blasts, a generator of rotational motions) and by natural sources (e.g. local earthquakes, rockbursts etc.).


The frame of the instrument is a solid rigid body adapted so that it can be easily attached to the ground motion of which is measured. Advantageously, it can have the shape of a disc or cylinder, for example. Typically, its dimensions are within decimetres to meters, usually within 1 m. Its weight enables easy transfer and manipulation and for that reason it is typically made of light metals (e.g. duralumin). Seismic sensors are mounted at various points on the frame and are of two types, vertical and horizontal, according to the seismic motion component they measure. The horizontal sensors have varying orientations so that it is possible to derive from them the waveform of two mutually perpendicular horizontal seismic components. The lowest number of sensors that need to be deployed on the frame for measuring three translational and three rotational components using a calibration based on the frame rigidity is 4 vertical sensors and 4 horizontal sensors. Nevertheless, it is advantageous to use a higher, even number of sensors that are arranged in parallel pairs.


The primary outputs of the seismic sensors are signals from vertical and horizontal sensors, e.g. geophones. The sensor outputs do not represent the real ground motion, however, because they are influenced by the frequency characteristics of the sensors. The goal is to measure the real ground motion in a certain frequency band. For that reason, the signals from the sensors are filtered with a band filter and are corrected with regard to the frequency characteristics.


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Kontakt

Ing. Evžen Ondráček

Business Development Manager

Telefon:

+420 224 491 362




Poslední změna: 16. listopad 2017 14:52 
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Univerzita Karlova

Ovocný trh 560/5

Praha 1, 116 36

Česká republika


Identifikátor datové schránky: piyj9b4

IČO: 00216208 

DIČ: CZ00216208


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