List of Post-Doctoral Fellowships (archive) ****************************************************************************************** * Archive - projects announced in 2019 ****************************************************************************************** Applicants could apply in 2019 for positions (available from 1. 1. 2020) in projects annou faculties/institutes: ****************************************************************************************** * Center for Economic Research and Graduate Education (CERGE) ****************************************************************************************** Title of the research project: Economics of Innovation, Economic Geography, and Applied Econometrics CERGE UK seeks a postdoctoral candidate with focus on theoretically and empirically orient in microeconomics, economics of innovation, economic geography or applied econometrics. Pr be given to candidates pursuing research spanning across the above fields. Applicants shou the capacity to pursue a research project at the frontier of current knowledge as well as achieve a strong publication record in leading scholarly journals. ****************************************************************************************** * Third Faculty of Medicine ****************************************************************************************** Title of the research project: 1. Mechanisms of action of ADP-dependent hexokinases on the cellular metabolism Background: Glucose phosphorylation is needed for all the modes of glycolysis; thus, hexok as key enzymes needed for a sufficient energy supply in human cells. In contrast to the be ATP-dependent hexokinases, multiple organisms, including humans, express ADP-dependent hex the function of which is poorly understood. Despite that the function of ADP-dependent hex neglected, their presence in multiple taxa suggests their evolutionarily conserved role in metabolism. Available evidence suggests their mutation in multiple cancers, which also cal exploration of their role in aerobic glycolysis. The proposed study of genetically enginee of ADP-dependent hexokinases should contribute essential fragments of the mosaic of cellul in health and disease, and make it less puzzled. Recently, we formed a pipeline allowing e straightforward analysis of enzyme kinetics of ATP-dependent hexokinases. We also substant the precision of the state-of-the-art prediction methods, which are to be used in the prop There is a synergy with institutional projects funded by the University, which already led of a series of genetically engineered cell lines with the expression of ATP-dependent hexo by means of the CRISPR/Cas9 technology and allowed to conduct detailed analyses of diabete associated variations in hexokinases. This post-doc position is aimed to build upon these uncover the roles of ADP-dependent hexokinases in human cell metabolism in health and dise this post-doc project are to be set up based on the interaction with the candidate and bas prior wet lab experience. Supervisor: RNDr. Petr Heneberg, Ph.D. Workplace: II. Internal Clinics 2. Re-harvesting split thickness skin grafts in extensively burned patients: molecular mec and new therapeutic approaches of the donor site Annotation: Although the increased risk of mortality at specialized burn centers represent over 60% of total body surface area (TBSA) (Jeschke et Herndon 2014), burn injury has rema leading cause of unintentional injury and death in children less than 9 years of age (Palm first step of severely burned patient management involves burn shock fluid resuscitation b of intravascular volume leading to adequate organ perfusion with several specific modifica management of pediatric patients (Romanowski et Palmieri 2017). The second step includes s period that may take months (Herndon 2017). Whereas the epidermis represents the primary barrier between outer and inner environments, components contribute to the mechanical, viscoelastic, functional and cosmetic properties resulted scars (Wainwright et Bury 2011). Therefore deep burns, following excision of the covered only with split-thickness skin grafts (STSG) may tend to contract while defects re thickness transplants demonstrate improved function and appearance. The most widely used a artificial skin is Integra® that is composed of porous matrix of cross-linked bovine tendo glycosaminoglycan (chondroitin 6-sulfate) covered by a semi-permeable silicone layer (Yann Yannas et al. 1980; Dagalakis et al. 1980; Yannas et al. 1981; Burke et al. 1981: Heimbach The major issue of treatment in extensively burned patients represents rapid wound closure harvesting has remained the hallmark of skin repair where the intervals between procedures to 6 weeks and depend on patient’s condition (Barret-Nerin, Juan; Herndon, David N. 2004). sites as well as poor wound healing of the donor area increase the time period between rep and prolong overall treatment. Furthermore, with increasing time of donor area regeneratio frequency of serious complications such as infection and/or poor wound healing. From this swift and efficient healing of the donor area is mandatory te improve healing and, thus cl with the possibility of repairing in particular large body areas. In present case we have that re-harvesting the scalp was possible within 12 days following complex treatment strat NASC covered with XD whereas the routinely Grassolind® dressed donor site took 45 days to other donor areas were than covered with the biological sandwich technique and re-harveste 6 — 10 days. Since the history of Prague Burn Centre is closely connected with the development and clin of advanced biological wound dressing techniques, including keratinocytes cultured on acel (Matouskova et al. 1997; Dvorankova et al. 2003; Zajicek et al. 2011). In present project firstly plan to evaluate in cooperation with Institute of Molecular Genetics whether the e profiles and course of skin healing at the STSG donor sites changes or remains its charact with increasing number of repeated harvesting. Secondly, in cooperation with the Technical Liberec and Institute of Organic Chemistry and Biochemistry we plan to develop and test on animal models and patients new active wound dressings preventing infections and improving the STSG donor site. Supervisor: MUDr. Robert Zajiček, PhD. Workplace: Prague Burn Centre ****************************************************************************************** * Faculty of Medicine in Plzeň ****************************************************************************************** Title of the research project: 1. Characterising immune cells in colorectal tumors AIM: to assess composition of cytotoxic and immune inhibitory cells in precursor tumors to cancer (adenomas), in colorectal cancer and adjacent healthy mucosa and lastly in metastas will help to understand the role of various immune cells at different phases of tumor deve BACKGROUND: Mounting evidence indicates that the immune system plays a key role in protect cancer. Animal and human studies demonstrate that, under the pressure of immune surveillan tumor cells tend to selectively accumulate traits that help them evade immune destruction. immunogenic tumor in an immunocompetent host may result in optimal stimulation of the immu and elimination of the tumor. Alternatively, mutated tumor cells selectively develop varia have acquired insensitivity to immunologic surveillance (e.g., through increased tumor-ind immunosuppression) and that can expand in an unrestrained fashion. A general deterioration individual’s immune defense may contribute to tumor escape. During first-line anti-tumor i nascent tumors may be detected by lymphocytes of the innate immune system – including natu (NK) cells, monocytes, and natural killer T cells – which may lead to the destruction of s cells, uptake and processing of their fragments by macrophages and dendritic cells, and se inflammatory cytokines that attract further immune effector cells to the tumor site. Prese associated antigens to naive CD4+ T helper cells and CD8+ T cells activates adaptive immun activated and antigen-specific cytotoxic T cells expand and home in to the tumor microenvi facilitating tumor cell death. In general, cytotoxic CD8+ T cells and Th1-type CD4+ T (hel exhibit antitumor activity. By contrast, FOXP3 expressing Tregs and myeloid-derived suppre suppress anti-tumor responses and promote tumor progression and metastasis. Natural killer are sub-classified by their expression of CD56 and/or CD16 cell surface markers, and inclu and immune inhibitory subtypes. Immune cell types can be identified by immunohistochemistr targeted to specific surface markers of these cells. METHODS: The present project involves establishment of an immunohistochemical staining bat detection of the key immune cell types in pathological slides and frozen tissue samples. T be applied on colorectal cancer related samples, maintained in Pilsen. These include fresh and adjacent mucosal samples, metastatic tumor samples and polyps of early adenomas. The r composition are correlated with clinical and prognostic data. Department: Biomedical Center, Faculty of Medicine in Pilsen, Charles University Laboratory: Laboratory of Cancer Treatment and Tissue regeneration Supervisor: Václav Liška, M.D., Ph.D., Associate Professor of Surgery Title of the research project: 2. Hydrogen sulfide signaling leads to SIRT1-established epigenetic code in mammalian oocy The state of the art: Hydrogen sulfide is a recently highlighted member of the gasotransmitter family, which rel been elucidated even in mammalian oocyte.1,2 One of hydrogen sulfide’s molecular actions c S-sulfhydration, hydrogen sulfide-derived post-translational modification, modulating the and structure of various proteins. Based own recent knowledge, hydrogen sulfide leads to i activity of histone deacetylases, through S-sulfhydration. Accordingly, there is possible action leading to epigenetic code, dynamically changed in oocyte and early embryonic devel understanding of this molecular action offers the unique opportunity for further medical r knowledge transfer to Reproductive Medicine.4 References: 1. Nevoral, J. et al. PLoS One 9, (2014). 2. Nevoral, J. et al. Nitric Oxide - Biol. Chem. 51, (2015). 3. Adamkova, K. et al. J. Anim. Sci. Biotechnol. 8, 83 (2017). 4. Nevoral, J., Bodart, J.-F. & Petr, J. Oxid. Med. Cell. Longev. 2016, 1730750 (2016). Additional information at: www.biomedic-plzen.cz/en/404-laboratory-of-reproductive-medicine [ URL "http://www.biomedi en/404-laboratory-of-reproductive-medicine"] Department: Biomedical Center, Faculty of Medicine in Pilsen Laboratory: Laboratory of Reproductive Medicine Supervisor: Jan Nevoral, Ph.D. 3. Impact of diabetes mellitus to autonomic nervous system innervating cardiovascular syst Input premise Diabetes mellitus is a disease with high incidence and high socio-economic relevance. The diabetes mellitus is an alarming global health issue. The cardiovascular system is among t functional and structural impairment during progression of this disease are limiting for l survival. Scientific activities of Laboratory of Laser Microdissection are mainly focused on study o different physiological and pathological states on the heart innervation. The research pro find mediators or their receptors responsible for symptoms of diabetic or cirrhotic cardio Methodological approaches, also, include analysis of gene expression and protein tissue di by means of RT-qPCR, Western blot, and immunofluorescence in separate heart compartments a ganglia. Additionally, laser microdissection is used in order to analyze effect of mention cardiac ganglia. The research will be focused on autonomic nervous system innervating the heart and vessels I and type II diabetes mellitus on these structures will be studied in animal models by me PCR, immunohistochemistry and Western blotting. Department: Biomedical Center, Faculty of Medicine in Pilsen Laboratory: Laboratory of Laser Microdissection Supervisor: Magdaléna Chottová Dvořáková, M.D., Ph.D., Associate Professor of Physiology ****************************************************************************************** * Faculty of Arts ****************************************************************************************** Title of the research project: Middle Ages in an Interdisciplinary Perspective The Centre for the Study of the Middle Ages (css.ff.cuni.cz) is seeking a highly qualified post-doc researcher who would join the interdisciplinary team of medievalists at the Centr years. The applicant should have a manifest interest in applying interdisciplinary approac applicant should present an innovative project proposal in any aspect of medieval studies, go beyond a concrete case study. A particular motivation for conducting research in Prague collaboration with a particular researcher from the Centre for the Study of the Middle Age specific sources not available elsewhere) will be considered an asset. In addition to purs own research agenda, the researcher will take active part in the Centre?s endeavors. Based field, the researcher will be integrated into the relevant department of the Faculty of Ar expected to take part in the activities of the department, too. The researcher is expected to take part in teaching and run four seminars per academic yea and a research based on the expertise and interests of the researcher each semester). The researcher is expected to publish at least two high quality articles in a database jou Web of Science) per academic year. Submitting a project application on behalf of the Facul ERC) will be considered an asset. The researcher is also expected to take part in organizi collaboration in medieval studies at the faculty. Salary: ca. 2,000 EUR Department: Centre for the Study of the Middle Ages Supervisor: Jan Čermák ****************************************************************************************** * Faculty of Education ****************************************************************************************** Title of the research project: 1. Professional vision of future teachers (noticing and knowledge-based reasoning) Pre-service teachers must develop a range of skills, including a certain type of noticing different from lay people’s skills. When observing a mathematics lesson, either live or on are expected to notice aspects of the lesson that are deemed important for the development knowledge. Yet the complexity of a mathematics lesson is such that if they direct attentio they do so at the expense of something else. Much research has been undertaken in recent y on what it is that student teachers do and do not notice in a mathematics lesson, how they it and how their professional vision (noticing ability and knowledge-based reasoning) can In the Department of Mathematics and Mathematical Education, we have used and investigated reflection based programmes such as Lesson Study and video-clubs. Thus, we offer a coopera aimed at reflection-based teacher education in general and on the possibilities of video-b the development of professional vision in particular. Workplace: Department of Mathematics and Mathematical Education Contact person: doc. RNDr. Naďa Vondrová, Ph.D. Title of the research project: 2. Communication in and about mathematics teaching and learning Communication between actors in mathematics classrooms represents one of the important iss not only the course of lessons but also their outputs. There are various variables whose r teaching and learning process can be researched, e.g., the type and form of questions pose the participation of individual actors or groups of actors in the communication, the activ of actors in the communication, the organization of the lesson supporting pupils’ creative of interdisciplinary approach etc. One of components of the communication in a classroom i used as language of instruction. Nowadays, many pupils are taught mathematics in a languag their mother tongue. It concerns both teaching mathematics to a linguistically homogeneous and Language Integrated learning or bilingual education) or heterogeneous classes (e.g. mi pupils). Thus, we offer a cooperation on research aimed at communication in mathematics lessons in teaching in a foreign language and in multicultural contexts in particular. Department: Department of Mathematics and Mathematical Education Contact person: doc. RNDr. Naďa Vondrová, Ph.D. Title of the research project: 3. Biotechnology and Ethics: Central Europe Teacher Candidates’ Opinions about Eugenics Biotechnology in connection with ethics is important topic of present-day science. Develop biotechnologies using affecting the genomes of different organisms have raised need to sol communicate numerous problems of ethical status of eugenics. Whereas genetics is an integr science (biology) curriculum at ISCED 2 and ISCED 3 schools, it is important for teachers´ know opinions of prospective science (biology) teachers in order to effectively implement genetics or didactics courses. Department: Department of Biology and Environmental Studies Contact person: RNDr. Lenka Pavlasová, Ph.D. Title of the research project: 4. Measurement of non-cognitive skills among students: the use of the anchoring vignette m Non-cognitive skills like persistence, reliability, and self-discipline strongly influence decisions and also affect wages, as stated by the Nobel prize laureate James Heckman. In c educational research, there is a growing body of studies dealing with the measurement of n skills and also the comparison of non-cognitive skills among different groups of students. of non-cognitive skills are based on self-assessment questions in questionnaire surveys. H been shown that the accuracy of self-reported data can be hindered by the differences in t groups of students use scales. For example, two students with the same actual level of sel self-assess their self-discipline differently: one student can assess his/her self-discipl the other student as average. It is crucial to take these differences in the scale usage a groups of students (cultures, countries, socio-economic groups, etc.) into account since t to misleading results. Innovative methodological approaches have been proposed to solve problems with scale usage methods is the anchoring vignette method. The Educational Research Anchors Center at the D Education in the Faculty of Education of the Charles University (contact researcher: Hana on the statistical development of this method and also the use of this method in the field research. We have published several innovative studies using the anchoring vignette method the following topics: students’ motivation to learn, school discipline, students’ ICT self students’ English language self-assessment, students’ life satisfaction, teacher classroom and teacher support behavior. We also received grant support for our research from the Cze Foundation. We currently seek an excellent postdoctoral researcher who would cooperate with us on the measurement of students’ non-cognitive skills and the use of the anchoring vignette method research. We require excellent knowledge of both quantitative and qualitative research met and experience with measurement of non-cognitive skills. Department: Department of Education Contact person: doc. RNDr. PhDr. Hana Voňková, Ph.D. et Ph.D. Title of the research project: 5. Assessment of student teachers at the end of their studies The research will focus on the current ways of assessment of teacher trainees at the end o Teachers in the Czech Republic complete their university degrees as fully qualified teache evaluation should reflect theoretical knowledge as well as student teachers' performance i resemble the current and future teaching practice as much as possible. Implemented approac continuously evaluated. This research will focus on the development of research tools and evaluation of existing practice in the student teachers´ assessment. Department: Department of Pre-primary and Primary Education Contact person: PhDr. Jana Stará 6. Value added assessment in education, longitudinal data analysis and structural equation on CLoSE datas The Czech Longitudinal Study in Education (CLoSE) realized by Institute for Research and D of Education, at Charles University offer a rich panel data of about 6000 students for ana links between cognitive and non-cognitive outcomes of students at the level of lower-secon secondary education (age 11-18). Data follow on cohort of 4th graders from TIMSS&PIRLS 201 allow also for international comparison. The aim of post-doc position will be to work in t analysis of various research questions related to CLoSE data, with an emphasis on students motivation and other student level variables in a Czech school system that uses early trac achievement. Sampling allows to compare academic track with mainstream education. At the s analysis of classroom climate and its relation with students achievement and grades in Mat and Reading will be also in focus. We currently seek an excellent postdoctoral researcher to apply advanced statistical analysis (preferably using R, MPlus software) of longitudina sciences. Department: Institute for Reserach and Development of Education Contact person: David Greger, Ph.D. ****************************************************************************************** * Faculty of Science ****************************************************************************************** Title of the research project: 1. Modelling and laboratory investigation of bentonite for nuclear waste repositories Postdoctoral position in geology in Prague, Czech Republic Hypoplastic model for unsaturated expansive clays has recently been implemented into an in element code SIFEL developed at Czech Technical University. It has been used successfully behaviour of bentonite buffer in planned nuclear waste repositories. Recently a European f project BEACON has been setup to investigate the process of homogenization of bentonite bl to guarantee adequate sealing properties of the buffer. In the proposed project it is plan investigate the behaviour of the buffer in laboratory experiments and to numerically model Laboratory testing will be performed on newly acquired THM unsaturated oedometric apparatu to perform tests up to 150 °C. Numerical modelling will be done using SIFEL finite element hypoplastic constitutive model. The project will thus stimulate both laboratory and numeri applicant, while he will have a freedom to decide specific orientation of the project depe interests. Minimal salary: equivalent of 2000 EUR/month Workplace: Institute of Hydrogeology, Engineering Geology and Applied Geophysics, Charles Faculty of Science Project supervisor: doc. RNDr. David Mašín, Ph.D Title of the research project: 2. The role of gut microbiota in the evolution of murine rodents Project description: Based on the hologenome theory, animal genomes and metagenomes of their microbiota co-evol their fitness is aligned as they form a joint phenotype, the holobiont. It follows that ho evolution can play important role in many evolutionary processes, including speciation. It clear how well the hologenome theory assumptions fit mammals-gut micriobiota relationship. We study gut microbiota evolutionary patterns across a wide range of rodent phylogeny – Mu We also focus on the role of gut microbiota in speciation by studying its composition and across two rodent hybrid zones. Important novelty of our project lies in extending the hol to gut bacteriophage community. Bacteriophages represent important regulators of gut micro divergence of this community across different host species has not been studied yet. Our r by Czech Science Foundation project no. 19-19307S: „Evolutionary patterns of gastrointesti murine rodents example“ Research goals: The postdoctoral researcher will integrate metagenomic data from wild rodent populations t vivo laboratory experiments to study: 1) gut microbiota evolutionary patterns across Murinae subfamily 2) possible role of gut microbiota in speciation in murine hybrid zones 3) maternal and social transmission of bacteriophage community 4) co-evolutionary links of bacteriophage community to murine hosts and their gut microbio The researcher will participate on study design, experimental procedures, data analyzes as the preparation of publication outputs. Detailed focus of the posdoctoral project will be considering her/his previous expertise and research interests. Requirements: We are looking for a highly motivated postdoctoral researcher with both theoretical and pr in microbiology, evolutionary biology and/or community ecology. Experience with (meta)geno analyzes, independent creative thinking and significant background in statistical modeling desirable. Minimal salary: equivalent of 2000 EUR/month Department: Department of Zoology, Faculty of Science Contact (for informal inquires): Jakub Kreisinger (PI of the project) Title of the research project: 3. Bioelectroanalytical Methods for High-Throughput Screening and Sensitive Determination Pollutants Rapid in situ monitoring of detrimental organic xenobiotic compounds in both the living an environment is one of the most important tasks of modern analytical chemistry. Electrochem being connected with modern flow injection or batch injection sampling systems, become sui for high-throughput screening of electrochemically active xenobiotics because they are ine sufficiently sensitive, and they present an independent alternative to so far prevalent sp and separation assays. Additional added value is obtained by combining electrochemical tec biorecognition elements (DNA, enzymes, antigens/antibodies) and various signal-enhancing n provide highly sensitive and selective electrochemical biosensors for environmental toxici The aim of the proposed post-doc project is the preparation, development, and subsequent t new electrochemical (bio)sensors for high-throughput screening and sensitive determination environmental pollutants (chemical carcinogens, pesticides, drugs, etc.). Flow injection a and/or batch injection analysis (BIA) are planned to provide fast sampling systems for ele detection, where non-traditional electrode materials (e.g., silver amalgam, boron-doped di structured forms of carbon) will be used for construction of newly designed miniaturized d Special attention will be paid to increasing sensitivity and selectivity of the developed using: (i) utilization of host–guest interactions between the analyte and the biorecogniti enzyme, antigen/antibody), (ii) incorporation of various signal-enhancing nanomaterials (c nanostructures, metal nanoparticles) on the electrochemical transducer surface, and (iii) modern preliminary separation and preconcentration techniques (micro solid-phase extractio micro-extraction, gas-diffusion micro-extraction, hollow-fiber extraction). Minimal salary: Equivalent of 2000 EUR/month Workplace: UNESCO Laboratory of Environmental Electrochemistry, Department of Analytical C of Science, Charles University, Hlavova 8, 128 43 Prague 2, Czech Republic Contact person and supervisor of the project: Assoc. Prof. RNDr. Vlastimil Vyskočil, Ph.D. Title of the research project: 4. Synthesis of Chiral Helical Hydrocarbons for Material Science Chiral helical compounds are a class of aromatic hydrocarbon substances with defined 3D st are potential advanced intermediates for preparation more complex compounds with potential organic electronics and optics. The project is focused on development of new class of such compounds: helical 5,8-di(spiro indeno[2,1-c]fluorenes (DSFIF) and their helical congeners with extended ?-systems. These combine properties of helicenes (aromatic compounds with a rigid helical scaffold) and com spiro-junction (so called spiro effect that essential for desirable photopoptical properti fluorescence). As the main route to this class compounds will be explored intramolecular catalytic cyclot by using chiral transition metal complexes that should yield directly products with the de scaffold. Further transformations should give rise to the target aromatic compounds. The i of the project will be also studies regarding evaluation of their optophysical, as well as properties (tunable fluorescence emission, quantum yields, emission of circularly polarize These studies will performed with the in house equipment. As far as other synthetic modifi concerned, it is expected to expand the developed methodology for synthesis of the hithert helically chiral metalloorganic compounds that should have improved optophysical propertie experiments by using model compounds have provided sufficient evidence to confirm feasibil project: a) cyclotrimerization proceeds with high yields, b) the products are highly fluor products are configurationally stable, d) they emit circularly polarized light, and last b the target compounds can be access with high overall yields in 5-6 steps. Minimal salary: equivalent of 2000 EUR/month Workplace: Faculty of Science, Department of Organic Chemistry, Charles University Project supervisor: Prof. RNDr. Martin Kotora, CSc Title of research project: 5. New deglaciation chronology of the North American Ice Sheet Complex Abstract: The North American Ice Sheet Complex (NAISC) covered northern North America during the las largest ice mass in the Northern Hemisphere, the NAISC was the main contributor to the lat level rise and its meltwater was implicated in the abrupt climate fluctuations at the Plei transition. Moreover, the NAISC formed the main obstacle on the route along which the huma Americas. Since the publication of the last NAISC deglaciation chronology 15 years ago, ne cosmogenic nuclides exposure dating and optically stimulated luminescence, allow for direc ice retreat instead of dating the onset of the deposition of organic material (as with C-1 also become available on the extent of the ice sheet, in particular for the areas of the c This has significantly changed the view of the NAISC at the Last Glacial Maximum compared 2000s when the last version of the ice retreat chronology was published. It is therefore t a new ice margin chronology for the NAISC. Objectives: - To produce a new ice margin chronology for the NAISC using radiocarbon, cosmogenic nucli optically stimulated luminescence ages. - To reconstruct not only the best estimate but also the minimum and maximum extent for ea order to adapt the data for use in numerical modelling. Salary: equivalent of 2000 EUR/month Workplace: Department of Physical Geography and Geoecology Project supervisor: Martin Margold Title of the research project: 6. Reverse engineering of ribosomal peptidyl transferase center Postdoctoral position in biochemistry in Prague, Czech Republic A postdoctoral position is available at a research group at Faculty of Science of Charles in Prague (located at a new campus in Biocev, www.biocev.eu). The group is focused on prot evolution and the studied themes are very interdisciplinary with relevance in origins of l astrobiology. The goal of the postdoc project will be protein reverse evolution of the mos ribosomal part, the peptidyl transferase center (PTC). The postdoc will be expected to per bioinformatic analysis of the available structural data of this region, to design and work protein libraries using synthetic biology approaches and perform structural/functional cha protein-RNA complexes. Minimal salary: equivalent of 2000 EUR/month Department: Department of Cell Biology, Biocev Campus, Charles University in Prague, Facul Project supervisor: Klára Hlouchová PhD ****************************************************************************************** * Faculty of Mathematics and Physics ****************************************************************************************** Title of the research project: 1. Call for PostDoc Position in the area of Interval methods for global optimization Post-doc position for one-year period from 1st January 2020 Research Project Applications are invited for a postdoc position at Department of Applied Mathematics, Char in Prague, Czech Republic. The position is for one year, and the starting date is January possibility of one renewal. Interval methods play a crucial role in designing algorithms for solving global optimizati They are used for handling numerical errors, finding bounds on objective functions, comput enclosures of nonconvex functions, and reduction of feasible domain, among many others. Th this project will be conducted in particular in some of the following directions: - interval linear algebra for global optimization - properties of interval matrices, complexity issues - theory and methods for checking properties of functions on feasible domains - convex underestimators and the corresponding relaxation properties - investigation of enclosing objects, relaxation on these objects Candidates should have a completed PhD in Mathematics or Computer Science, and demonstrate for excellence in research. It is expected to have strong background in optimization. Skil computation, matrix analysis, operations research and programming are appreciated as well. Contact person: doc. Mgr. Milan Hladík, Ph.D., Charles University, Faculty of Mathematics Department of Applied Mathematics Title of the research project: 2. Call for PostDoc Position in the area of Mathematical analysis of models of chemically Post-doc position for one-year period from 1st January 2020 Research Project We look for a postgradual research fellow to join the project focused on mathematical anal of partial differential equations describing chemically reacting mixtures. A PhD. degree in mathematical analysis or applied mathematics connected with mathematical partial differential equations is required, knowledge in continuum mechanics, thermodynami is welcome. The project will be supervised by Dr. Milan Pokorný, associate professor at the Mathematic Charles University together with dr. Michal Pavelka from the same institute. Contact person: doc. Mgr. Milan Pokorný, Ph.D., Charles University, Faculty of Mathematics Mathematical Institute of Charles University Title of the research project: 3. Call for PostDoc Position in the area of Banach Space Theory – Descriptive Set Theory Post-doc position for one-year period from 1st January 2020 Research Project Applications are invited for a postdoc position at Department of Mathematical Analysis, Fa Mathematics and Physics, Charles University, Czech Republic. We look for a postgradual res join the group of researchers at Department of Mathematical Analysis working in Banach Spa Descriptive Set Theory. A Ph.D. degree in a related field is required. The research of thi focus on the following topics and their mutal relationships: - Ramsey Theory, - definable equivalence relations, and - geometry of Banach spaces. Candidates should demonstrate strong potential for excellence in research. The project wil by Miroslav Zelený, associate professor at Faculty of Mathematics and Physics, Charles Uni with Jiří Spurný, professor at the same department. Contact person: doc. RNDr. Miroslav Zelený, Ph.D., Charles University, Faculty of Mathemat Department of Mathematical Analysis Title of the research project: 4. Call for PostDoc Position in the area of Quantum Gravity and Analogs Post-doc position for one-year period from 1st January 2020 Research project The Bekenstein bound on the entropy of any physical system, never greater than the entropy black hole (BH), indicates that the ultimate fundamental Hilbert space might be finite dimensional, see, e.g., [1]. Recently, implications of the latter for BH evapora considered by our research group at the Faculty of Mathematics and Physics of Charles Univ to a picture where both fields and spacetime are emergent phenomena [2]. Such picture is i might find realization in certain condensed matter analog systems, such as Dirac materials research line initiated by our group (see [3], for a review, and [4], for some recent resu The post-doctoral scholar we are seeking, will be working in this area. Henceforth, the id to show proved expertise of the foundational issues of quantum field theory, both in its condensed matter and particle physics declinations, both in curved and flat spaceti directions are currently being developed, and the candidate will be exposed to all of them Nonetheless, one specific and particularly important line we would like to pursue with her to the inequivalent quantizations occurring for different phases of matter, see, e.g., [5] Indeed, a milestone theorem of quantum mechanics (Stone-von Neumann) establishes that, for of freedom, all representations of the canonical commutations (quantizations) are equivale unitary transformation. For quantum fields, being the number of degrees of freedom infinit can be overcome. Thus, the infinite degrees of freedom allow for spontaneous symmetry breaking, hence for different, non equivalent phases stemming from th Hamiltonian/Lagrangian. In particular, when such representations are those associated to an inertial frame, one, and to an accelerated frame, the other, we know that the above non manifests itself as the Unruh effect [6]. This is at the root of phenomena like the Hawkin turn, of the BH thermodynamics. Within this scenario, the candidate will focus on the puzz how the nonequivalent quantizations, necessary for the Hawking phenomenon, could arise eve fundamental system has a finite number of degrees of freedom, as the Bekenstein bound appe to imply [1]. [1] J. D. Bekenstein, Universal upper bound on the entropy-to-energy ratio for bounded sys D 23 (1981) 287; R. Bousso, The holographic principle, Rev. Mod. Phys.74 (2002) 825. [2] G. Acquaviva, A. Iorio, M. Scholtz, On the implications of the Bekenstein bound for bl evaporation, Ann. Phys. 387 (2017) 317. [3] A. Iorio, Curved spacetimes and curved graphene: A status report of the Weyl symmetry Mod. Phys. D 5 (2015) 1530013. [4] A. Iorio, P. Pais, (Anti-)de Sitter, Poincar, Super symmetries, and the two Dirac poin Ann. Phys. 398 (2018) 265. [5] N. N. Bogolyubov, A. A. Logunov, A. I. Oksak, I. T. Todorov, General principles of qua theory, Kluwer, 1990; H. Umezawa, Advanced field theory: Micro, macro, and thermal physics Phys., 1993. [6] L. C. B. Crispino, A. Higuchi, G. E. A. Matsas, The Unruh effect and its applications, 80 (2008) 787; S. Takagi, Vacuum noise and stress induced by uniform accelerator: Hawking- Rindler manifold of arbitrary dimensions, Prog. Theor. Phys. Suppl. 88 (1986) 1. Contact person: doc. Mgr. Alfredo Iorio, Ph.D., Charles University, Faculty of Mathematics Institute of Particle and Nuclear Physics Title of the research project: 5. Call for PostDoc Position in the area of Low Temperature Physics and Superfluidity Post-doc position for one-year period from 1st January 2020 Research Project Superfluid helium has many unique properties among which is the existence of quantum turbu category of flows bearing striking similarities to classical turbulence while differing dr other aspects. Quantum turbulence may be probed, e.g., by visualization techniques, by ded such as second sound generators/detectors, or using micro- and nano- scale mechanical reso proposed research project is focused on the applications of such resonators to probe quant in superfluid 4He at very low temperatures down to 10 millikelvin, reached on a dilution r At higher temperatures, traditional techniques such as second sound attenuation will be us further insight. The successful candidate will join the superfluidity group in Prague, and will be primaril for the design and operation of cryogenic experiments related to investigations of quantum in superfluid 4He using nanowires and other lithographically produced structures as part o research activities. Applicants with a background in numerical simulation will be encourag our previous work on modeling of quantum turbulence using the vortex filament technique. A training in nanofabrication techniques is feasible in collaboration with our partners. An applicant should have a doctoral degree in physics, cryogenics, fluid dynamics, or rela Previous experience with low temperature experiments is highly recommended. The candidates familiar with: - Low temperature experimentation, cryogenics (previous work on superfluidity is an advant - Basic electronics-related skills, standard lab instrumentation and automation techniques programming is an advantage) - Systematic data analysis using tools such as Python or Matlab Informal inquiries concerning the position are welcome, specific suggestions for research candidates will be considered as well. Contact person: prof. RNDr. Ladislav Skrbek, DrSc., Charles University, Faculty of Mathema Department of Low Temperature Physics Title of the research project: 6. Call for PostDoc Position in the area of Studies of jets and charmonia in heavy-ion col Large Hadron Collider Post-doc position for one-year period from 1st January 2020 Research project Heavy-ion collisions at the Large Hadron Collider (LHC) allow to study a hot and dense mat quarks and gluons, which is often called quark-gluon plasma (QGP). The QGP is similar to a in early stages of the evolution of universe. Studying QGP should bring better understandi strong interaction that are currently not understood from the first principles, such as th quarks and gluons to hadrons or collective aspects of strong interaction. Two broad classes of phenomena were observed in heavy-ion collisions which can be highligh them are flow-like phenomena which are observed as significant azimuthal anisotropies of s production. The flow phenomena are universally present in proton-proton, proton-ion, and i collisions. Flow phenomena are related to collective aspects of strong interaction and are modeled using tools of relativistic fluid dynamics. Second class of phenomena are quenchin which are observed as significant suppression of production of high transverse momentum je showers of hadrons) and various particle species. The quenching phenomena persist to unexp energies of a TeV scale and reflect the microscopic parton dynamics. More recently, LHC en brought possibility to study processes in electromagnetic interactions of ultra-peripheral collisions. This brought the first direct observation of the light-by-light scattering and more stringent limits to production of axions, new hypothetical particles predicted by som aiming to address physics beyond the Standard model of particle physics. The team at Charles University works on analyses mainly involving jets and charmonia using the ATLAS experiment. In the past ten years, the team has lead or significantly contribute key measurements in the field of heavy-ion collisions done using ATLAS, namely measurement asymmetry, measurements of the inclusive jet production, and measurements of the jet fragm team also works on phenomenological modeling of jet quenching and charmonia suppression as developing new methods for efficient mitigation of large backgrounds present in both proto heavy-ion collisions at the LHC. The candidate is expected to contribute to the phenomenological modeling of jet quenching suppression as well as to the effort of analyzing the data from the ATLAS experiment. The expected to have a PhD degree in the field of high-energy physics or high-energy nuclear p programming skills in C++ and Root. Contact person: doc. Mgr. Martin Spousta, Ph.D., Charles University, Faculty of Mathematic Institute of Particle and Nuclear Physics ****************************************************************************************** * Faculty of Social Sciences ****************************************************************************************** Title of the research project: 1. Al and social sciences, joint research project of Institute of Communication Studies an Institute of Political Studies In an effort to establish and further develop expertise in the nexus between Al and social Department of Journalism and the Department of Security Studies jointly seek a post-doctor in this field. The candidate is expected to exhibit a proven track-record linked to one or following themes: artificial intelligence, machine learning, big data — all in relation to social science(s). In the aforementioned context, the preferred research focus could inclu media, disinformation, propaganda, political revisionism or radicalization. We seek innova with experimental leanings, willing to cross disciplinary boundaries, and especially able divide between the technological and the social domains. Expected outcomes of the post-doc include two high-quality journal articles (Jsc or Jimp), involvement in the training of Ph and mutually enriching interaction with other members of the participating departments. Up agreement, the post-doctoral fellow will also have an opportunity to be involved in teachi the participating departments specifically envision a general course on Al-social domain n science (B.A.) and a more specialized course reflecting the principal research focus of th Contact: doc. Mgr et MgA. Filip Lab, Ph.D Title of the research project: 2. International relations in the time of uncertainty During several previous decades, world politics rested on an evolving, but still rather pe of an international order. This order was to a large extent based on the dominant position States (USA). Yet it also involved several important normative elements, represented by li intensive global economic cooperation, or international institutions. To a high extent, th was sustained by the demand coming from the other states, which saw it as an enabling arra dealing with global problems such the spread of weapons of mass destruction, terrorism, gl crises, or environmental degradation. At this moment, this order that has so far characterized international politics is facing important challenges. One of the factors that weaken it is the increasing activism and inf of the developing countries. Those countries often hold different views about the appropri international order, putting a greater emphasis on the principles of sovereignty and justi arrangement is also questioned by the changing distribution of power in the international by the decreasing position of the USA and the strengthening of the so-called rising powers least, a part of the turbulent development can be attributed to social and ideological cha in the developed countries. Within this topic, we are searching for a post-doc candidate that would identify and explo issue that has to do with the contemporary transformative processes in international polit candidate should definitely dispose with a strong theoretical and methodological backgroun background should enable him/her to contribute to the international academic debates. As f research topic, we are rather flexible. The concrete topic would need to be in some way co changing characteristics of world politics. In this context, we welcome proposals that may cooperative, as well as conflictual aspects of world politics. In terms of issue areas, we consider proposals that may be concerned with security issues, international economic rela other substantive field of the contemporary international relations. Contact: doc. PhDr. Jan Karlas, M.A., Ph.D. Title of the research project: 3. The Dynamic of Relations of the Visegrad Countries with Israel following the Rise of Na in Central Europe, Institute of International Studies This project aims to analyse current foreign-policy relations between the Visegrad countri following the rise of nationalist parties in the region. Since 1990, relations between the European countries have been intense. Especially the Czech Republic and Poland have a very of cooperation with Israel in various fields, including defence and security. Among the EU Central European countries are considered to be in the camp of pro-Israeli countries. Afte the nationalist parties in Hungary and Poland, the relations with Israel became more compl one hand, a strong focus on security, an ethnic character of a state, and anti-Muslim posi nationalist parties make Israel their natural partner. On the other hand, controversial pa especially a position of Polish and Hungarian populations towards the Jews during the Holo after the end of World War II, an aim to get a support among voters with nationalist, and Semitic, inclinations have a negative impact on the bilateral relations with Israel. The r Polish government to return private Jewish property, the law criminalizing certain stateme to Poles and Poland during World War Il, so-called the Holocaust Law, or a negative recept new Holocaust museum in Budapest among Hungarian Jews and international Jewry who criticiz whitewash and rewrite history concerning Hungary’s role in the murder of Jews during WWII, which had a negative impact on the bilateral relations with Israel. Contact: doc. PhDr. Tomas Nigrin, Ph.D. Title of the research project: 4. Postdoc in Economics, Institute of Economic Studies We are looking to hire a postdoc in the field of economics to carry on research activities following topics: public economics, international economics, development economics, econom political economy, and public finance. The postdoc will be part of the Institute of Econom Faculty of Social Sciences, Charles University and will become an active member of the Ins as the broad economics and finance community at Charles University. In addition, the postd teaching and research activities of the department. Charles University currently ranks in global top 100 in Economics, top 200 in Finance (bot Ranking's Global Ranking of Academic Subjects 2018), and 111th in Economics and Business ( Global Ranking of Universities 2019). For an overview of the Institute Economic Studies, k http://ies.fsv.cuni.cz Starting date: January 1, 2020. The candidate should hold a Ph.D. in Economics by the date of the application or at least scheduled until the end of October 2019. The funding is for 2 years. Applications include market Paper, a short research statement, a single letter of reference, and a copy of the a document about dissertation defense. Deadline for applications is July 19, 2019. Candida available for a Skype interview. Contact: Mgr. Petr Jansky, M.Sc., Ph.D. Title of the research project: 5. Current Development of Democracy in Central Europe - New Phenomena, New Approaches, Ins Sociological Studies During the first twenty years following the revolutions in Central Europe (here in the sen Visegrad countries) in 1989, we witnessed and analysed the consolidation of democracy (con stabilization of institutions, the institutionalisation of the parties and the party syste During this period, political science research focused mainly on questions such as transfo the communist regime to democracy, on Europeanisation, and so on. But during the last deca approximately by the beginning of the economic and financial crisis, but also strongly inf migration crisis, we face some new questions. Therefore, we are provided with the opportun new themes and to change the scope of research. New phenomena have developed within the fo countries, including but not limited to novel concepts such as illiberal democracy; or som such as populism in its various forms. We are searching for a post-doc candidate that would focus on the general topic of the evo Europe from one or more national point(s) of view. The candidate should focus on specific large phenomenon, such as political institutions in a broad sense, political actors (espec parties) and political processes (including for instance the depoliticization of societies The candidate should be equipped with a strong theoretical and methodological background a field research in the considered countries. We can consider comparative research with some Western European cases, but the crux of the research has to lay within the Central Europea Contact: doc. Michel Perottino, Ph.D. ****************************************************************************************** * Faculty of Law ****************************************************************************************** Title of the research project: Climate change and the Law The Faculty of Law of Charles University seeks a highly qualified postdoctoral candidate w in environmental law research, especially focusing on the area of legal issue related to c Climate change is an important task of contemporary environmental law research, requiring knowledge in many fields. Applicants should demonstrate their understanding of the complex recognized legal issue and consequently their ability of the interdisciplinary approach to The research itself should cover all legal tasks related to responding to climate change. expected to examine the legal aspects of climate change mitigation (reducing), focusing on energy law, as well as climate change adaptation, focusing on the legal measures to adapt forest, water and soil to the changing climate. This newly opened postdoctoral position is fully scientific and research, tightly connecte publication activity, thus a strong ability of publishing in scholarly journals is presume outcome of the two-years stay at the Faculty of law shall be an extensive monograph. The r expected to actively participate in the activities of the Department of Environmental Law part in teaching. The candidate should be entirely concentrated on the research with no wo than her or his work at the Faculty. Workplace: Department of Environmental Law of the Faculty of Law Supervisor: Prof. JUDr. Milan Damohorský, DrSc. ****************************************************************************************** * Post-doc positions at CEFRES ****************************************************************************************** CFA: TWO POST-DOCTORAL POSITIONS AT CEFRES – CHARLES UNIVERSITY Two post-doctoral positions at CEFRES cofounded by the Charles University Deadline for submission: 2 August 2019 Period: January 1, 2020 - December 31, 2021 Application Language: English Address for submission: jerome.heurtaux@cefres.cz (please copy the email to adela.landova@ Two post-doctoral researchers will be recruited from January 1, 2020 for two years at CEFR both affiliated to CEFRES and to a relevant department for their research at Charles Unive doctoral researchers will be recruited on the basis of the quality of their research proje The results will be published in October 2019. Title of the research project: 1. CEFRES research areas The first post-doctoral position is intended for researchers whose research project can be CEFRES’s three research areas: Research area 1 – Displacements, “Depaysements” and Discrepancies: People, Knowledge and P "http://www.cefres.cz/en/157"] Research area 2 – Norms & Transgressions [ URL "http://www.cefres.cz/en/163"] Research area 3 – Objects, Traces, Mapping: Everyday Experience of Spaces [ URL "http://ww en/169"] For equal scientific quality, preference will be given to a project on the social, economi transformations of contemporary Central Europe. Title of the research project: 2. Research project: TANDEM program A specific competition to recruit a second post-doctoral researcher whose work covers one possible topics listed below. The selected candidate will work in association with a resea the Czech Academy of Sciences (CAS) and a researcher assigned by the CNRS within the frame program [ URL "http://www.cefres.cz/en/10344"] . Topic 1: "Adverbial Experience: The Aesthetics of Contemporary Czech and French Art" This research project will associate the post-doctoral researcher with CAS researcher Tomá (Institute of Philosophy, Czech Academy of Sciences). Description: The project will focus on contemporary art (literature, music, plastic art, p from the perspective of today aesthetics. The candidate will work in the domain of aesthet history of art. Applicants may contact Mr. Koblížek before applying for any relevant questions on their ap Koblizek[at]flu.cas.cz. Topic 2: "Peace and Environment: Alain Touraine, Eastern Europe and Analysis of Social Mov Communism" This research project will associate the post-doctoral researcher with CAS researcher Doub (Institute of Contemporary History of the CAS). Description: Candidates from across social sciences and humanities are invited to explore in Eastern Europe in the second half of the 20th century. They can also dedicate their res Touraine’s research under the perspective of sociology or history of science. Applicants may contact Ms. Olšáková before applying for any relevant questions on their ap olsakova[at]usd.cas.cz. Topic 3: " The Europe of Resentment and Rubble: a Confederation of the Vanquished?" This research project will associate one post-doctoral researcher with CNRS researcher Mic (Institute of Political Social Sciences, University Paris Nanterre). Description: Mapping interior frontiers, silenced pasts and living memories of displaced p (European) minorities (ie. Sudeten and Bukovina Germans, Ukrainians from Poland, Italians Europeans of Algeria...). Applicants may contact Ms. Mich?le Baussant before applying for any relevant questions on at michele.baussant[at]cnrs.fr. Application Package Applicants must submit the complete application package consisting of the following elemen The application form duly filled in: download HERE [ URL "UKEN-1325-version1-02_applicatio application form includes the description of the research project which must: • Specify the name of the TANDEM research project or the CEFRES research area you want to explain how your research befits it. • Include an explanation on the methodology and inputs of your own research, as well as a bibliography (max. 1 page-long). • Include expected outcomes (publications, conferences, and so forth): • A letter of reference from the former PhD supervisor: download HERE [ URL "UKEN-1325- version1-03_letter_of_reference.doc"] . The letter must mention the title of the PhD, th defence etc. • A detailed CV • A list of publications • A copy of the PhD diploma Application packages must be submitted by August 2, 2019 electronically in an e-mail entit NAME_CEFRES-UK” at: jerome.heurtaux@cefres.cz (send a copy to his assistant: adela.landova Please send the application form in both PDF and as a Word-document. Applicants are welcom PIs of the research projects they apply to before sending their application. Eligibility Criteria • be high-level young researchers from abroad (non-Czech), who defended their PhD no more prior to the application deadline in a university outside the Czech Republic • conducting a research befitting one of the research projects described above (or CEFRES • good command of English is mandatory Framework of the Charles University (UK) and CEFRES co-financed post-doctoral position As a partner of CEFRES Platform, Charles University recruits 2 high-quality post-doctoral who are non-Czech and you have defended their dissertation outside the Czech Republic. The assigned to CEFRES, within the frame of the Charles University’s International Post-Doc Re These two positions are renewable one-year fixed-term contracts and start on 1 January 202 The gross monthly salary is 32 000 CZK. UK-CEFRES post-doctoral researchers will be affili CEFRES and a relevant department of one of the faculties in social sciences and humanities University according to their main discipline. They are expected to: • contribute through their own research to the research project they apply to • take part in the scientific life of CEFRES • submit a yearly report on their research advances to the director of CEFRES • come to live in Prague from 1 January 2020.