Prof. MUDr. Aleksi Šedo, DrSc., FCMA ****************************************************************************************** * Vice-Rector for Development ****************************************************************************************** rozvoj@prorektor.cuni.cz [ URL "mailto:IT@prorektor.cuni.cz"] +420 224 491 299 Rectorate of Charles University Ovocný trh 560/5 116 36 Praha 1 Education and Academic Degrees • DrSc Oncology, Charles University, 2000 • CSc Medical Chemistry and Biochemistry, 1st Faculty of Medicine, CU, 1990 • MUDr General Medicine, Faculty of General Medicine, CU, 1986 • Appointed Professor at CU in the field of Biochemistry and Pathobiochemistry, 2002 • Habilitation in Medical Biochemistry, 1st FM CU, 1996 • Clinical Specialization: Board Certification in Internal Medicine 1995 Employment, Academic and Professional Career • 2025 – present Head of the Institute of Biochemistry and Experimental Oncology, 1st FM C • 2007 - present Head of the Institute of Biochemistry and Experimental Oncology, 1st FM C • 2002 – present Professor of Medical Chemistry and Biochemistry, Institute of Biochemistr Experimental Oncology, 1st FM CU • 2020 – 2023 Vice-Dean for International Relations, 1st FM CU • 2020 - 2021 Deputy Minister of Health • 2012 - 2020 Dean, 1st FM CU, Prague • 2005 – 2012 Vice-Dean for Grants and Development, 1st FM CU, Prague • 2002 – 2014 Head of Tumour Cell Biology Laboratory (joint unit of IMG CAS and 1st FM CU) • 1997 - 2001 Associate Professor of Medical Chemistry and Biochemistry, 1st Institute of Chemistry and Biochemistry, 1st FM CU. • 1999 – 2002 Senior scientist Procter & Gamble, Corporate R&D Europe, Schwalbach Technica Germany and Cincinnati USA • 1996 – 1999 Scientist, Procter & Gamble, Corporate R&D Central Europe, Praha • 1994 – 1995 Institut Curie, Unite 365, Paris, associate scientist (Association du Recher France) 6 months; • 1993 – 1999 Institute of Experimental Medicine CAS, Researcher • 1993 - 1999 Resident, Emergency Physician, 1st Internal Clinic, University Hospital, 1st • 1992 - 1993 Visiting Scientist (12 months) a Visiting Professor (6 months), Institute of and Mutagenesis, CNR, Pisa, Italy • 1987 - 1991 Researcher, Research Institute of Tuberculosis and Respiratory Diseases, Pra Courses • 1989 Int. Union Against Tuberculosis and Lung Diseases: Applied Immunology and Histochem • 1995 EMBO: Methods in Cell Biology; Epithelial cell polarity. Heidelberg • 1999 Lifescience Partnering Forum. Institute of Management, Germany, Heidelberg 1999 • 2000 Creative Problem Solving, ? CSF Group Bufallo; Brussels Scientific and Healthcare Projects • Investigator of numerous national and international grant projects (e.g. Grant Agency of Internal Grant agency of Ministry of Health, Czech Health Research Council, Ministry of Bilateral grant of Italian CNR-1st.Faculty of Medicine, Charles University, Prague) etc, of several international projects (e.g. 6FP SSA No 512153, Lifescihealth –1, NHR Dev Tox member of the Executive board of EATRIS-cz consortium, Operational Programme RDE Ministr Youths and Sports project “Centre of Cancer Ecology”, • Organizer and lecturer of Europe Against Cancer 4EU+ Summer Schools (Sorbonne, Warsaw, M • Head of the National Institute for Cancer Research, Project no.: LX22NPO5102 governing b Education, Youth, and Sports of the Czech Republic, financed by the European Union – Nex as part of the Czech Recovery Plan Roles in Doctoral Study Programs • Guarantor of doctoral studies “Experimental and Clinical Oncology” at Charles University • So far supervisor of 9 PhD graduated students, consultant-supervisor of 1 PhD graduate, progress • Member of Area Boards in Biochemistry and Pathobiochemistry (CU) and Molecular Medicine University) Memberships in Institutions, Expert Panels, Scientific Councils(selected) • 2023 – present Member, Horizon Europe Programme Committee – EU Mission on Cancer • 2023 – present Member, European Association for Neuro-Oncology (EANO) General Board • 2023 – present EANO Scientific Committee • 2021 – present Deputy Coordinator, Oncology Science Area Council, Cooperatio CU • 2019 – present Member, Scientific Board of Grant Agency of Czech Republic (GAČR) • 2019 – present Member, Scientific Board of Masaryk Memorial Cancer Institute, Brno • 2018 – 2020 & 2022 Member, Scientific Board of Ministry of Health of CR • 2017 – present Chair, Ministry of Health of CR Committee for Institutional Support of Re • Organizations • 2017 – present Member, Editorial Board of Drugs & Forensics Bulletin, National Drug Enfo • Agency • 2016 – present Member, Scientific Board of AGEL (provider of health care services in CR) • 2015 – present Member, Czech Medical Academy (FCMA) • 2014 – present Member, Scientific Board of CU • 2011 – present Chair and Founding Member, Neuro-Oncology Section of COS JEP • 2020 – 2021 Member, Committee for Healthcare Research Strategy (approved by Government o • 2014 – 2021 & 2023 Member, Presidium of the Czech Health Research Council • 2020 – 2021 Member, National Crisis Management Team of CR • 2020 – 2021 Member, EC ad hoc group ERAvsCORONA • 2018 – 2020 Member, Guarantee Commission for Clinical Guidelines Project • 2017 – 2019 Member, Scientific Board, Aesculap Academy BBraun, Prague • 2017 – 2023 Member, Scientific Board of the Faculty of Medicine, Masaryk University • 2017 – 2020 Founding Chair, Association of Deans of Medical Faculties in CR • 2013 Expert Panel Member, “Health Protection and Promotion” – National Priorities of • Research, Development and Innovation • 2012 – present Member, Scientific Board of 1st FM CU • 2012 – 2016 Member, Internal Grant Agency Scientific Board, Ministry of Health of CR • 2006 – 2008 Chair, GAČR Subcommittee 301 • 2005 – 2007 Member, GAČR Subcommittee 301 • 2005 – 2008 Member, GAČR Medical Sciences Committee • 1996 – 2000 Expert Group Member, Parliamentary Subcommittee for Science and Higher • Education • Member of the Monitoring Committee and Scientific Board of CU Infrastructure Development Albertov" • Board Member, Biotechnology and Biomedicine Center in Vestec BIOCEV (EU Structural Funds • Executive Board Member, EATRIS Infrastructure • Expert reviewer for domestic and international grant agencies and journals • Expert witness in litigation case '13CV1346 DMS NLS – UNITED STATES DISTRICT COURT SOUTH CALIFORNIA, regarding gliptin use risks, USA Awards • 2020 Gold Medal of CU • 2017 Silver Medal of CU • 2016 Arnošt of Pardubice Award – for outstanding contribution to education at CU, Prague • 2015 Bedřich Hrozný Award for Creative Act – CU, Prague • 2015 Award of the Board of CLS JEP for best book publication • 2013 Award of the Czech Society for Oncology for best publication • 2011 Medal of the 1st Faculty of Medicine, CU • 2005 Award for best publication, Czech Rheumatology Society • 1992 Gold Medal, World Invention Exhibition EXPO '92 International Collaborations(selected, publication- and project-based only) University of Palermo (Italy), University of Antwerp (Belgium), SUNY – Dept. of Medicine/M (USA), ExxonMobil (Belgium), Harvard Medical School/Dana-Farber Cancer Institute (USA), Fe Ltd (UK), Probiodrug AG (Germany), Sorbonne University, Nencki Institute Warsaw, Universit (Australia), Stanford University Professional Focus • Biochemistry, Cell Biology, Experimental Oncology; Regulation and Signaling of Cell Prol Differentiation; Membrane Proteases and Non-Hydrolytic Functions; Proteases in Cancer Di Therapy; Advanced Models in Cell Biology; Innovative Diagnostic and Therapeutic Oncology • Approximately 130 IF publications (mostly first or corresponding author), ~3000 citation 25; numerous invited lectures, including plenary sessions (Finland, Germany, USA, Japan, Slovenia, UK, Greece, etc.) • President of the 20th Congress of the European Association for Neuro-Oncology, 2025 • Co-author of multiple patents, including international ones • Monographs and Book Chapters (editor and author; e.g., Glioma Cell Biology, Springer Sci Press, Technet, etc.); Editor of Special Issues: Frontiers in Bioscience (2019), Frontie "Diffuse Glioma Microenvironment: Insight into Cancer Ecology" (2021) • Experience in Academic and Industrial Research Management, Technology Transfer, Intellec Protection, and Public-Private Partnerships in Biomedical Research and Education (medica medical), laboratory medicine, doctoral studies in biomedicine