It enhances its international prestige by extending cooperation in science and research. To do this, it uses the CU International Advisory Board to direct its scientific work, the European Centre for engagement in international scientific networks and funding, and actively participates in international research infrastructures through various educational and scientific programmes.
Charles University also engages in the transfer of knowledge and technologies with the aim of fulfilling the university's third role and increasing its competitiveness. This activity is ensured by the Centre for Knowledge and Technology Transfer (CPPT) and Charles University subsidiary company Charles University Innovations Prague (CUIP).